59 research outputs found

    Do You Have Food $ense?: Utilizing Community Partnerships to Reduce Food Insecurity and Improve Health Behaviors

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    The purpose of this program is to develop a collaborative partnership between OSU Extension Family and Consumer Sciences (FCS) and a Interparish Ministries Mobile Food Pantry to address a 12 percent increase in the number of individuals seeking food assistance between 2014 and 2015, as reported by Supplemental Nutrition Assistance Program (SNAP) and local food pantry usage data. Both organizations are bonded by common missions striving to eliminate multiple daily struggles for limited resource families living in areas where access to affordable and nutritious food is limited. The aim of the program is to educate participants from a faith-based mobile food pantry about the importance of planning and preparing nutritious meals. Instruction is based on the principles from MyPlate Food Guide and also incorporates information from Extension's SNAP-Ed lesson plans. The informal atmosphere of the sessions encourages participants to openly share personal experiences about providing and preparing food for their own families while reducing food insecurity. The program consisted of six theme sessions held June-November 2017. The sessions provided an opportunity for group discussion focusing upon a designated topic and incorporated participant's input reflecting ways to improve current choices emphasizing healthier lifestyle choices. Teamwork was emphasized between Extension educators and SNAP-Ed program staff building a program delivering a meaningful message that participants can immediately put into practice. The local team not only includes the Extension FCS educator and SNAP-Ed staff, but the Agriculture and Natural Resources educator and the Master Gardener Volunteer program. Evaluation includes both pre- and post-assessment data. Evaluations revealed both knowledge and food preparation skill gains. Participants documented success stories include: "practiced canning skills learned during class in their home kitchens, tasted new foods and incorporated them into weekly family menus, enjoyed sharing and talking about my personal cooking experiences with others and numerous requests for another series offered next summer."AUTHOR AFFILIATION: Margaret Jenkins, The Ohio State University Extension Educator, Family and Consumer Sciences, Clermont County, [email protected] (Corresponding Author); Mona Glover, SNAP-Ed Program Assistant, The Ohio State University Extension, Clermont County; Danielle Combs, SNAP-Ed Program Assistant, The Ohio State University Extension, Clermont County.Learn how community partnerships can be used to influence and change health behaviors among limited-resource audiences. Program participants learn through "dialogue approach to adult learning" including hands-on food preparation and food tastings. The presenters will demonstrate the teaching technique outlined in Norris' From Telling to Teaching resource. Program goals, methods, recruitment, lesson topics and evaluation will be shared

    Association of Left Atrial Function Index with Atrial Fibrillation and Cardiovascular Disease: The Framingham Offspring Study

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    BACKGROUND: Left atrial (LA) size, a marker of atrial structural remodeling, is associated with increased risk for atrial fibrillation (AF) and cardiovascular disease (CVD). LA function may also relate to AF and CVD, irrespective of LA structure. We tested the hypothesis that LA function index (LAFI), an echocardiographic index of LA structure and function, may better characterize adverse LA remodeling and predict incident AF and CVD than existing measures. METHODS AND RESULTS: In 1786 Framingham Offspring Study eighth examination participants (mean age, 66+/-9 years; 53% women), we related LA diameter and LAFI (derived from the LA emptying fraction, left ventricular outflow tract velocity time integral, and indexed maximal LA volume) to incidence of AF and CVD on follow-up. Over a median follow-up of 8.3 years (range, 7.5-9.1 years), 145 participants developed AF and 139 developed CVD. Mean LAFI was 34.5+/-12.7. In adjusted Cox regression models, lower LAFI was associated with higher risk of incident AF (hazard ratio=3.83, 95% confidence interval=2.23-6.59, lowest [Q1] compared with highest [Q4] LAFI quartile) and over 2-fold higher risk of incident CVD (hazard ratio=2.20, 95% confidence interval=1.32-3.68, Q1 versus Q4). Addition of LAFI, indexed maximum LA volume, or LA diameter to prediction models for AF or CVD did not significantly improve model discrimination for either outcome. CONCLUSIONS: In our prospective investigation of a moderate-sized community-based sample, LAFI, a composite measure of LA size and function, was associated with incident AF and CVD. Addition of LAFI to the risk prediction models for AF or CVD, however, did not significantly improve their performance

    Processing Speed Mediates Age Cohort and Prospective Memory Performance

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    Age has been shown to negatively impact prospective memory (PM), the ability to carry out intentions in the future. However, many age-related cognitive changes may reflect underlying declines in processing speed (Salthouse et al., 2004). The purpose of this study was to investigate whether processing speed mediates the relationship between age cohort and prospective memory performance. Older (n = 52) and younger adults (n = 40) completed WAIS-IV Coding and the Virtual Kitchen Protocol, which includes PM tasks with both time-based and event-based cues both in and out of virtual reality. Processing speed mediated the relationship between age cohort and PM performance both in and out of virtual reality. Partial mediation was observed in the analog-based PM, whereas full mediation was observed in the virtual reality-based PM. Processing speed may explain age-related changes in PM as measured by both analog and virtual reality tasks

    Trypanosoma brucei BRCA2 acts in a life cycle-specific genome stability process and dictates BRC repeat number-dependent RAD51 subnuclear dynamics

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    Trypanosoma brucei survives in mammals through antigenic variation, which is driven by RAD51-directed homologous recombination of Variant Surface Glycoproteins (VSG) genes, most of which reside in a subtelomeric repository of >1000 silent genes. A key regulator of RAD51 is BRCA2, which in T. brucei contains a dramatic expansion of a motif that mediates interaction with RAD51, termed the BRC repeats. BRCA2 mutants were made in both tsetse fly-derived and mammal-derived T. brucei, and we show that BRCA2 loss has less impact on the health of the former. In addition, we find that genome instability, a hallmark of BRCA2 loss in other organisms, is only seen in mammal-derived T. brucei. By generating cells expressing BRCA2 variants with altered BRC repeat numbers, we show that the BRC repeat expansion is crucial for RAD51 subnuclear dynamics after DNA damage. Finally, we document surprisingly limited co-localization of BRCA2 and RAD51 in the T. brucei nucleus, and we show that BRCA2 mutants display aberrant cell division, revealing a function distinct from BRC-mediated RAD51 interaction. We propose that BRCA2 acts to maintain the huge VSG repository of T. brucei, and this function has necessitated the evolution of extensive RAD51 interaction via the BRC repeats, allowing re-localization of the recombinase to general genome damage when needed

    Development of a measure of model fidelity for mental health Crisis Resolution Teams

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    Background Crisis Resolution Teams (CRTs) provide short-term intensive home treatment to people experiencing mental health crisis. Trial evidence suggests CRTs can be effective at reducing hospital admissions and increasing satisfaction with acute care. When scaled up to national level however, CRT implementation and outcomes have been variable. We aimed to develop and test a fidelity scale to assess adherence to a model of best practice for CRTs, based on best available evidence. Methods A concept mapping process was used to develop a CRT fidelity scale. Participants (n = 68) from a range of stakeholder groups prioritised and grouped statements (n = 72) about important components of the CRT model, generated from a literature review, national survey and qualitative interviews. These data were analysed using Ariadne software and the resultant cluster solution informed item selection for a CRT fidelity scale. Operational criteria and scoring anchor points were developed for each item. The CORE CRT fidelity scale was then piloted in 75 CRTs in the UK to assess the range of scores achieved and feasibility for use in a 1-day fidelity review process. Trained reviewers (n = 16) rated CRT service fidelity in a vignette exercise to test the scale’s inter-rater reliability. Results There were high levels of agreement within and between stakeholder groups regarding the most important components of the CRT model. A 39-item measure of CRT model fidelity was developed. Piloting indicated that the scale was feasible for use to assess CRT model fidelity and had good face validity. The wide range of item scores and total scores across CRT services in the pilot demonstrate the measure can distinguish lower and higher fidelity services. Moderately good inter-rater reliability was found, with an estimated correlation between individual ratings of 0.65 (95% CI: 0.54 to 0.76). Conclusions The CORE CRT Fidelity Scale has been developed through a rigorous and systematic process. Promising initial testing indicates its value in assessing adherence to a model of CRT best practice and to support service improvement monitoring and planning. Further research is required to establish its psychometric properties and international applicability

    Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial

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    Background Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy

    Bone turnover is adequately suppressed in osteoporotic patients treated with bisphosphonates in daily practice

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    <p>Abstract</p> <p>Background</p> <p>Monitoring osteoporosis therapy by measurement of bone turnover markers (BTMs) might detect non-compliance in an earlier stage of anti-osteoporosis treatment and improve persistence.</p> <p>Methods</p> <p>BTMs were measured in two groups. The first group consisted of patients newly diagnosed with osteoporosis and starting treatment. We observed which proportion of patients had a decrease of serum levels of procollagen type 1 N-terminal propeptide (P1NP) and C-terminal crosslinking telopeptide (CTX) greater than the least significant change (LSC) after 3 months of treatment. Secondly, we determined which proportion of patients who were treated with bisphosphonates for ≥ 3 months reached the biological goal of therapy, BTMs in the lower half of the normal premenopausal range. P1NP and CTX were also measured in a reference population of 34 healthy premenopausal women.</p> <p>Results</p> <p>In the first group 31 patients were included, in 25 patients (81%) levels of both markers decreased with ≥ LSC, in the other patients a possible explanation was found.</p> <p>In the second group 95 patients were included, in 95% the serum P1NP levels and CTX levels were in the lower half of the premenopausal range. In 6 of the 7 patients with a level above the premenopausal range a possible explanation was found.</p> <p>Conclusion</p> <p>A decrease in bone turnover ≥ LSC can be observed in the majority of newly treated patients. In chronically treated patients, 95% have a bone turnover in the premenopausal range. In most patients with inadequate suppression of BTMs during bisphosphonate treatment, an explanation was found. Monitoring treatment effect with BTMs in daily practice is feasible, and might be an additive tool in improving therapy compliance.</p

    School Experiences of Children of Prisoners: Strengthening Support in Schools in England and Wales

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    Millions of children worldwide experience having their parents sent to prison every year (Penal Reform International 2017). Children who experience a parent spending time in prison, are more likely than any other group of children to face significant disadvantages including increased poverty rates; an increase in caring responsibilities; an increase in being bullied and stigmatisation; a decrease in school attendance and attainment; increased mental health problems and an increase in the risk of offending (Morgan & Gill 2013; Morgan et al 2013a; Morgan et al 2013b). Moreover, parental imprisonment has been shown to have a direct impact on children’s academic attainment as well as socio-emotional development often leading to changes in behaviour which may escalate to school exclusion or truancy (SCIE 2008). This chapter will explore the impact that parental imprisonment can have on children’s school experiences and offer recommendations to strengthen support in schools for this group of children
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